Understanding Jardiance and Its Effects on Urination

August 5, 2024

Jardiance (empagliflozin) is a medication commonly prescribed to manage type 2 diabetes. It belongs to a class of drugs known as SGLT2 inhibitors, which work by helping the kidneys remove glucose from the bloodstream through urine. While Jardiance is effective in controlling blood sugar levels, it can have notable effects on urination in both men and women. 

How Jardiance Works

Jardiance functions by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the kidneys. This prevents the reabsorption of glucose back into the blood, leading to its excretion through urine. As a result, patients on Jardiance typically experience increased urine output.

Effects on Urination

  • Increased Frequency: One of the most common side effects of Jardiance is increased urination (polyuria). This is a direct result of the drug’s mechanism, which causes the body to expel excess glucose through urine. Patients might find themselves needing to urinate more frequently than usual.
  • Dehydration: With the increased urine output, there is a higher risk of dehydration. Patients are advised to maintain adequate hydration by drinking plenty of fluids throughout the day.
  • Urinary Tract Infections (UTIs): Both men and women may have an elevated risk of developing urinary tract infections while taking Jardiance. The presence of excess glucose in the urine can create an environment conducive to bacterial growth, leading to UTIs. Symptoms of UTIs include a burning sensation during urination, frequent urge to urinate, and cloudy or strong-smelling urine.
  • Genital Infections: Women may experience an increased incidence of yeast infections, as the glucose-rich urine can promote yeast growth. Men can also develop genital infections, though it is less common.

Special Considerations for Men and Women

Men:

– Prostate Health: Men with existing prostate issues may notice an increase in urinary symptoms, such as difficulty starting urination or a weak urine stream. The increased urine output can exacerbate these symptoms.

– Genital Infections: Though less common than in women, men can develop fungal infections of the genital area.

Women:

– Higher UTI Risk: Women are generally more prone to UTIs, and this risk is further heightened with the use of Jardiance. Regular monitoring and prompt treatment of any signs of infection are crucial.

– Yeast Infections: Women should be vigilant for symptoms of yeast infections, such as itching, redness, and discharge, and seek treatment if these occur.

Managing Side Effects

– Hydration: Staying well-hydrated can help mitigate some of the dehydration risks associated with increased urination.

– Hygiene: Practicing good hygiene can help reduce the risk of UTIs and genital infections.

– Regular Monitoring: Regular follow-ups with your healthcare provider can help catch and manage any adverse effects early.

What Does This Mean for You?

Jardiance is an effective medication for managing type 2 diabetes, but it does come with potential urinary side effects. Patients should be aware of these effects and take proactive steps to manage them. If you experience any severe or persistent symptoms, consult with your healthcare provider to discuss your treatment options. At Austin Urology Institute, we are here to support you in managing both your diabetes and any urological concerns. 

Feel free to reach out to us for more information or to schedule an appointment.